Pro Picks: Week 11 NFL Matchups

The upcoming week in the NFL showcases some thrilling quarterback duels, as Russell Wilson faces off against Lamar Jackson for the top position in their division. Meanwhile, Josh Allen and Patrick Mahomes renew their competitive rivalry, with Jalen Hurts and Jayden Daniels gearing up for their own head-to-head encounter.

The spotlight in Week 11 is on a key AFC North matchup as Wilson leads the Steelers (7-2) against two-time MVP Jackson and the Ravens (7-3) on Sunday. Additionally, the unbeaten Chiefs (9-0) battle Allen and the Bills (8-2), who are currently at the top of the AFC East, in what will be a rematch from the playoffs.

The NFC East is in contention as the Commanders (7-3) visit the Eagles (7-2) to kick off the week on Thursday night.

BetMGM Sportsbook lists five road teams as favorites, including Baltimore, setting the stage for a compelling week of NFL action, and Pro Picks aims for another successful week.

Seattle (4-5) at San Francisco (5-4)

**Line:** 49ers minus 6 1/2
The Seahawks have yet to overcome the 49ers since Wilson’s departure, having lost six straight games against them, including a playoff matchup. Coming off a bye week, Seattle finds itself struggling after a promising 3-0 start with new coach Mike Macdonald. They boast the league’s top passing offense but have deficiencies on the defensive side. San Francisco welcomes back Christian McCaffrey and looks strong as they typically excel during this period, having gone 9-0 following byes in 2022 and 6-0 the prior season. Quarterback Brock Purdy has a stellar track record against Seattle.

**BEST BET:** 49ERS: 31-20

Cincinnati (4-6) at Los Angeles Chargers (6-3)

**Line:** Chargers minus 1 1/2
Cincinnati recently fell short against the Ravens, squandering a 14-point lead. Joe Burrow is fighting through turnovers but now faces a formidable Chargers defense that has been strong lately. The Chargers rank first in points allowed, while their star, Justin Herbert, benefits from a solid run game. The Bengals have fared well as underdogs; however, the Chargers have been reliable at home.

**UPSET SPECIAL:** BENGALS: 23-20

Washington (7-3) at Philadelphia (7-2)

**Line:** Eagles minus 3 1/2
A defining NFC East battle unfolds as Jalen Hurts and the Eagles aim for a sixth consecutive victory. Philadelphia showcases the league’s second-ranked defense and sixth-ranked offense. Washington’s revitalized team, led by rookie QB Jayden Daniels, has emerged as a scoring powerhouse. However, after conceding 28 points in a recent loss, they must respond sharply against Philly’s high-octane attack.

**EAGLES:** 29-24

Green Bay (6-3) at Chicago (4-5)

**Line:** Packers minus 6 1/2
After a week off, Green Bay seeks its first NFC North win of the season against a Bears team struggling amidst a three-game losing streak. Bears QB Caleb Williams is facing scrutiny after coaching changes, while Jordan Love has been inconsistent with turnovers. Historically, Green Bay has dominated Chicago in recent matchups, posing challenges for the Bears.

**PACKERS:** 24-16

Jacksonville (2-8) at Detroit (8-1)

**Line:** Lions minus 14
Despite a shaky outing with five interceptions, the Lions clinched a key victory against Houston. They can’t afford a slip against a struggling Jaguars team that is vastly underperforming this season. Jacksonville’s inability to secure close games has been evident, suggesting a rough road ahead against a relentless Lions squad.

**LIONS:** 31-16

Minnesota (7-2) at Tennessee (2-7)

**Line:** Vikings minus 6
The Vikings continue to thrive with a robust defense while the Titans grapple with internal struggles and inconsistent quarterback play. Sam Darnold’s recent performances cast doubt on his position as the starter, further complicating Tennessee’s efforts to compete.

**VIKINGS:** 23-16

Las Vegas (2-7) at Miami (3-6)

**Line:** Dolphins minus 8
Miami’s offense begins to find its rhythm, leading into a matchup against the Raiders, who are currently plagued by an inability to score. Following a bye week, Las Vegas will face Miami, which is eager to climb back into playoff contention, though challenges remain for the Dolphins with a demanding schedule ahead.

**DOLPHINS:** 23-16

Los Angeles Rams (4-5) at New England (3-7)

**Line:** Rams minus 4 1/2
The Rams look to recover from a missed opportunity against the Dolphins, matching up against a Patriots squad coming off a surprising win. Despite New England’s recent success, challenges persist as they adapt under new management, creating an intriguing matchup.

**RAMS:** 24-17

Cleveland (2-7) at New Orleans (3-7)

**Line:** Saints minus 1
Celebrated QB Jameis Winston returns to New Orleans with Cleveland, who is eyeing a comeback following a bye week. The Saints secured an unexpected win against the Falcons but remain inconsistent overall. Cleveland hopes for improvement from star running back Nick Chubb against a listless defense.

**BROWNS:** 20-17

Indianapolis (4-6) at New York Jets (3-7)

**Line:** Jets minus 3 1/2
Reinstating Anthony Richardson comes at a time when the Colts require a lift after a series of turnovers from Joe Flacco. The Jets are in disarray with insufficient offensive production, adding to the intrigue of this matchup.

**JETS:** 17-16

Baltimore (7-3) at Pittsburgh (7-2)

**Line:** Ravens minus 3
A fierce rivalry highlights this matchup as the Steelers dominate their recent history against Baltimore. Wilson, who has led Pittsburgh to three victories, takes on the potent Ravens’ offense. Jackson’s historical struggles against the Steelers add another layer of complexity to the game.

**RAVENS:** 24-23

Atlanta (6-4) at Denver (5-5)

**Line:** Broncos minus 2 1/2
The Falcons aim to recover after a disappointing game where missed opportunities hindered their performance. Denver, buoyed by strong defense, welcomes Atlanta as both teams jockey for playoff positioning. The outcome is pivotal for their seasons going forward.

**BRONCOS:** 24-20

Kansas City (9-0) at Buffalo (8-2)

**Line:** Bills minus 2 1/2
The Chiefs hang onto their perfect record, defying expectations alongside Mahomes’s underdog reputation. As they confront the Bills, who are experiencing one of their best starts historically, the stakes are especially high for both franchises.

**CHIEFS:** 22-20

Houston (6-4) at Dallas (3-6)

**Line:** Texans minus 7 1/2
After a disappointing performance, the Texans will look to regroup while facing a Cowboys team without starting quarterback Dak Prescott. This matchup significantly impacts their respective playoff hopes.

**TEXANS:** 27-16
Last week’s results included a successful straight-up record of 10-4 while performing against the spread at 9-5. The cumulative records led to strong performances overall, with notable successes in prime-time games and designated best bets.