HOUSTON — In a significant development for the Houston Texans, receiver Nico Collins will not be participating in the matchup against the Detroit Lions. Although there was optimism regarding his return to the field following his activation from injured reserve on Saturday, his absence will be felt as the Texans seek to recover from their recent defeat to the Jets.

On the Texans’ injury front, defensive end Will Anderson is also absent due to an ankle injury sustained in the previous game. In addition, running back Dameon Pierce will not be playing either, sidelined by a groin injury that had previously kept him out during the game against the Jets.

Meanwhile, the Lions will also see some changes in their lineup. Recently acquired pass rusher Za’Darius Smith, who joined Detroit through a trade with the Browns, is inactive for this game. Likewise, Lions tackle Taylor Decker is out, dealing with a shoulder injury that has hampered his ability to compete.

The Texans must strategize effectively without their leading receiver and key defensive players as they aim to turn their fortunes around against a competitive Lions team. The absence of both Collins and Pierce could pose challenges for Houston’s offensive strategy, while Detroit will look to capitalize on the opportunities presented by their opponents’ sidelined stars.