LONDON — In the latest round of the English League Cup, Premier League sides Brentford and Southampton successfully progressed to the quarterfinals after overcoming their second-tier challengers on Tuesday.

Brentford’s advancement came after a tense bout against Sheffield Wednesday, which culminated in a penalty shootout following a 1-1 deadlock in regulation time. The decisive moment was marked by goalkeeper Mark Flekken, who made a crucial save against Liam Palmer during the final penalty attempt, allowing Brentford to secure a 5-4 victory in the shootout.

Meanwhile, Southampton found a moment of relief in their campaign as James Bree netted a goal in the 88th minute to clinch a 3-2 victory over Stoke City. This win offers a much-needed boost for Southampton, who currently sit at the bottom of the Premier League standings.

The action continues with the remaining matches of the last-16 being held on Wednesday, featuring prominent teams across the league. Defending champions Liverpool will travel to face Brighton, while Premier League frontrunners Manchester City will take on Tottenham on the road. Additionally, there will be three other matchups between Premier League teams, including Newcastle facing Chelsea, Manchester United going up against Leicester, and Aston Villa clashing with Crystal Palace. Arsenal is set to visit second-tier Preston in another intriguing fixture.