See How Rosie O’Donnell Lost 100 Pounds Because of Mounjaro 

Key Points Summary – O’Donnell Lost 100 Pounds

  • Rosie O’Donnell stuns fans with her dramatic weight loss reveal.
  • Credits Mounjaro, a diabetes drug, for helping shed 100 pounds.
  • Lifestyle changes included cutting Diet Coke and cooking her own meals.
  • Moved to Ireland with her child, Clay, after Trump’s election.
  • Now wears a size large, down from XXL, and feels healthier.
  • Admitted to a lifelong battle with weight issues and past surgery.
  • Social media erupts with praise for her inspiring transformation.

O’Donnell Lost 100 Pounds: Star Unrecognizable After Stunning Weight Loss

Rosie O’Donnell just shocked the internet with a jaw-dropping photo of herself looking slimmer than ever. The comedian, 63, revealed her incredible transformation on Instagram—and fans can’t stop talking about it.

Mounjaro Miracle and Major Lifestyle Shift

O’Donnell shared a photo Friday holding a microphone onstage, looking significantly slimmer. Her caption? “i cant believe this is me now.”

The “View” alum says her transformation began two years ago when she started taking Mounjaro, a Type 2 diabetes medication known to curb appetite. Initially prescribed to manage her condition, the results were astounding.

By Christmas of that year, O’Donnell had already dropped 10 pounds. She gave up sugary drinks, including the six Diet Cokes she once consumed daily.

Life in Ireland, Life Without a Chef

Since moving to Ireland with her child Clay, O’Donnell says the weight has continued to melt off.

“I’ve lost more weight here,” she admitted in a recent TikTok video. Part of the reason? No more personal chef. Now she’s in charge of the kitchen and cooking daily meals for her and Clay.

She insists that shift, along with her ongoing use of Mounjaro, has made a major difference. Fans saw a slimmer, energized Rosie raving about her new lifestyle—and feeling healthier overall.

From XXL to Large: A New Wardrobe, A New Life

Gone are the elastic pants. While shopping at a Dublin boutique, O’Donnell said she was shocked to fit into size large clothes.

“It’s unbelievable to me. I was always XL or XXL. I haven’t shopped in a real store in years,” she shared.

More importantly, Rosie now says she sleeps better and feels more active. And the internet is loving the glow-up.

A Lifetime Battle with Weight

O’Donnell hasn’t hidden her past struggles. After a heart attack in 2012, she underwent vertical sleeve gastric surgery. That procedure helped her drop from 240 pounds to 176.

But it wasn’t enough to keep the weight off long term. Now, she says the combination of medical help and simple lifestyle tweaks is what truly worked.

“I cook. Eat less sugar. Drink only water. That’s what’s changed,” she told followers.

America’s Mounjaro Craze Grows

O’Donnell joins over 20 million Americans now taking weight loss medications like Mounjaro, Wegovy, and Ozempic.

Doctors say these drugs are changing the way people fight obesity. However, they also warn of side effects and stress that lifestyle changes remain essential.

Social Media Reacts to Rosie’s Transformation

Instagram blew up after her post went live. Thousands of fans flooded the comments section with praise, admiration, and congratulations.

“You look amazing!”

“You’re an inspiration, Rosie!”

“Thank you for being real about it.”

O’Donnell responded to several comments, thanking fans and joking about her new wardrobe needs.


O’Donnell Lost 100 Pounds
: Rosie’s Journey Continues

Despite the transformation, Rosie stays grounded. She reminds fans that weight loss is a journey—and hers is still unfolding.

“I still battle old habits. I’m still figuring this out. But I feel better. And that’s what matters,” she told her followers.

The media buzz shows no sign of slowing. With fans inspired and health experts watching, Rosie O’Donnell’s weight loss story may become a national blueprint for real, lasting change.

Rosie lost 100 pounds. But what she gained—health, energy, and confidence—may matter even more.

O’Donnell Lost 100 Pounds and found a whole new life. That’s one transformation America won’t forget.

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