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A groundbreaking study facilitates a cancer patient’s ability to speak with a rare voice box transplant

A man from Massachusetts has successfully regained his voice following a groundbreaking surgery at the Mayo Clinic in Arizona. Marty Kedian, 59, had his cancerous larynx removed and replaced with a donated one in a rare total larynx transplant procedure. This innovative approach, part of a new clinical trial, is aimed at offering more patients, including those with cancer, the opportunity to benefit from life-changing operations that involve larynx transplants.

The surgery, which took 21 hours, was facilitated by a team of six surgeons who transplanted the donated larynx along with surrounding tissues like thyroid and parathyroid glands. This procedure also involved connecting critical nerves to enable Kedian to swallow and move his vocal cords. Despite being hoarse, Kedian expressed his gratitude for being able to speak and communicate with his loved ones post-surgery.

According to Dr. David Lott, Mayo’s chair of head and neck surgery in Phoenix, patients who lose their larynx often face challenges in breathing, swallowing, and speaking, leading to a diminished quality of life. The study, which includes a small group of participants, aims to establish best practices for larynx transplants to expand this option to more individuals in need, bridging the gap for those who struggle to communicate due to laryngeal cancer or other conditions affecting the voice box.

While larynx transplants remain a rarity, the recent success in Kedian’s case marks a significant milestone in the field. Despite the challenges and risks associated with such complex surgeries, the potential benefits for patients like Kedian, who yearned to regain his voice to share bedtime stories with his granddaughter, underline the importance of ongoing research and medical advancements in this area.

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